Cortisol – catabolic or anabolic?

Cortisol – catabolic or anabolic?

By Sławomir Ambroziak

Keywords: cortisol, testosterone, catabolism, anabolism, receptors, transcription factors, coregulators, coactivators, corepressors, selective steroid receptor modulators, SERMs, SARMs, SVDRM, SGRM.

If testosterone is probably the most popular hormone amongst athletes, then cortisol – the most hated.

We all know that testosterone is an anabolic hormone that is one that stimulates muscle protein accumulation processes and thus contributes to muscle strength development and weight gain. On the contrary, cortisol is called a catabolic hormone that acts contrary to testosterone, interfering any positive effect of the latter on our muscles. więcej…

SECRECTS OF DHT

Keywords: DHT, testosterone, 5 alpha-reductase, aromatase, estradiol, 3 alpha HSD, 3 beta HSD, 3 alpha adiol, 3 beta adiol, isoflavones, androgenic receptors, alpha estrogen receptors, beta estrogen receptors.

Dihydrotestosterone (DHT) is a metabolite of testosterone – a major anabolic hormone that builds our muscles. The more testosterone in the body, the greater level of DHT. For years it has been believed that DHT has no effect on the muscles and is only responsible for the adverse effects of testosterone – seborrhoea, hair loss and prostate hypertrophy.

However, the results of new research and opinions of athletes seem to contradict those old beliefs… How would you explain the fact that the use of testosterone in conjunction with medications or supplements that inhibit its conversion to DHT gives weaker anabolic effects than the ‚pure testosterone treatment’, without similar extra supplementation…?

Does it mean there’s no alternative here? Do high testosterone level and superb muscles have to be associated with acne, male pattern baldness and problems with urinating?

więcej…

 

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